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Nodular and diffuse spindle cell infiltration in keloidal scleroderma: a case report.

Yiting Li1, Yibin Zeng2, Zile Chen1

  • 1Department of Dermatology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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|January 2, 2024
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Summary

Keloidal scleroderma presents as firm nodules, often mistaken for scars. This case highlights rare spindle cell infiltration, aiding accurate diagnosis of this scleroderma variant.

Keywords:
CD34case reportkeloidal sclerodermanephrogenic systemic fibrosisspindle cell infiltration

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Area of Science:

  • Dermatology
  • Pathology

Background:

  • Keloidal scleroderma is a rare scleroderma variant characterized by keloidal nodules or plaques.
  • Distinguishing keloidal scleroderma from hypertrophic scars or keloids can be challenging due to morphological and pathological similarities.

Observation:

  • This report details a unique case of keloidal scleroderma.
  • The histopathology revealed an unusual nodular and diffuse spindle cell infiltration.

Findings:

  • The presence of rare nodular and diffuse spindle cell infiltration is a key histopathological feature.
  • This specific infiltration pattern is not commonly associated with keloidal scleroderma.

Implications:

  • Recognizing this unusual histopathological finding is crucial for accurate diagnosis.
  • Enhanced understanding of keloidal scleroderma's varied presentations can prevent misdiagnosis.
  • Clinicians can improve diagnostic accuracy by being aware of these rare histopathological features.