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Associations between Chinese visceral adiposity index and risks of all-cause and cause-specific mortality: A

Xiaoyan Wu1, Chunqi Wang2, Deliang Lv1

  • 1Shenzhen Center for Chronic Disease Control, Shenzhen, China.

Diabetes, Obesity & Metabolism
|January 2, 2024
PubMed

Insights

The Chinese visceral adiposity index (CVAI) predicts mortality risk in Chinese adults. Higher CVAI is linked to lower cancer death risk but increased cardiovascular disease death risk.

Area of Science:

  • Public Health
  • Epidemiology
  • Cardiovascular Disease Research

Background:

  • Visceral obesity is a significant risk factor for mortality.
  • The Chinese visceral adiposity index (CVAI) is a novel indicator of visceral fat accumulation.
  • Understanding the association between CVAI and mortality is crucial for public health strategies.

Purpose of the Study:

  • To investigate the relationship between the Chinese visceral adiposity index (CVAI) and all-cause, cardiovascular disease (CVD), and cancer mortality.
  • To assess the predictive value of CVAI for mortality risks in a large Chinese adult population.

Main Methods:

  • A nationwide cohort study involving 3,916,214 Chinese adults.
  • CVAI calculated using age, BMI, waist circumference, triglycerides, and HDL cholesterol.
  • Cox proportional hazards regression models used to analyze mortality risks.

Main Results:

  • A U-shaped association was observed between CVAI and all-cause mortality.
  • Higher CVAI quartiles were associated with a reduced risk of cancer death but an increased risk of CVD death.
  • Subgroup analyses revealed J-shaped and inverted U-shaped relationships for mortality in younger adults (<60 years).

Conclusions:

  • The CVAI is a valuable and accessible indicator for predicting all-cause, CVD, and cancer mortality in Chinese adults.
  • CVAI has implications for health economics and secondary prevention strategies.
  • The CVAI may serve as a useful tool for early screening of mortality risks.
Abstract

Keywords:
CVD mortalityChinese visceral adiposity indexall-cause mortalitycancer mortalityprospective cohort study

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