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Adjunctive Diode Laser Therapy and Probiotic Lactobacillus Therapy in the Treatment of Periodontitis and Peri-Implant Disease
Published on: May 9, 2022
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Diode laser targeting red-complex bacteria in periodontitis: a systematic review
S Patel1, K H Awan, C M T Freitas
1College of Graduate Studies, Roseman University of Health Sciences, South Jordan, Utah, USA. spatil@roseman.edu.
European Review for Medical and Pharmacological Sciences
|January 2, 2024
Summary
Diode laser irradiation shows potential benefits when used with scaling and root planing for periodontitis. This adjunctive therapy may help reduce red complex bacteria and improve clinical outcomes, potentially decreasing the need for surgery.
Area of Science:
- Periodontology
- Laser Dentistry
Background:
- Periodontitis is characterized by inflammation and destruction of periodontal tissues, often associated with red complex bacteria.
- Diode lasers are explored for their antimicrobial properties and potential to improve periodontal parameters.
Purpose of the Study:
- To systematically review the effectiveness of diode laser irradiation as an adjunct to non-surgical periodontal therapy.
- To evaluate its impact on red complex bacteria levels, probing depth, and clinical attachment level.
Main Methods:
- Systematic review of randomized controlled trials identified through extensive database searches (Scopus, Embase, Medline, Web of Science).
- Primary outcome: reduction in red complex bacteria count; secondary outcomes: probing depth and clinical attachment level.
- Quality assessment using the Cochrane Handbook and ROB2 tool; exclusion of non-English articles.
Main Results:
- Eight studies with 210 participants were included, showing inconsistent results regarding diode laser's antimicrobial effect.
- Four studies found no significant difference in bacterial levels, while three reported significant reductions.
- Combined therapy showed a trend towards reduced bacteria and improved clinical parameters, though not always statistically significant.
Conclusions:
- The adjunctive use of diode laser in non-surgical periodontal therapy may offer benefits in reducing red complex bacteria and improving clinical parameters.
- Further high-quality research with objective measures is needed to establish definitive guidelines.
- This approach could potentially reduce the need for periodontal surgery.

