Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

[Isolation of functional bacteria guided by PCR-DGGE technology from high temperature petroleum reservoirs].

Huan jing ke xue= Huanjing kexue·2008

Same author

Assessing the spatial extent of breast tumor intrinsic optical contrast using ultrasound and diffuse optical spectroscopy.

Journal of biomedical optics·2008

Same author

alpha4/7-conotoxin Lp1.1 is a novel antagonist of neuronal nicotinic acetylcholine receptors.

Peptides·2008

Same author

[Construction and characterization of avian pathogenic Escherichia coli mutants with iro and/or tsh gene mutation].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology·2008

Same author

[Enhancement of GFP expression by Kozak sequence +4G in HEK293 cells].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology·2008

Same author

Sphingomyelin synthase 2 deficiency attenuates NFkappaB activation.

Arteriosclerosis, thrombosis, and vascular biology·2008

Search research articles

Related Experiment Video

Updated: Jul 6, 2025

Comparison of Three Clinical Stereoscopic Methods for Measuring Binocular Visual Function During Amblyopic Treatment in Unilateral Amblyopia

Comparison of Three Clinical Stereoscopic Methods for Measuring Binocular Visual Function During Amblyopic Treatment in Unilateral Amblyopia

Published on: September 27, 2024

Binocular Summation With Quantitative Contrast Sensitivity Function: A Novel Parameter to Evaluate Binocular Function

Xiaolan Chen¹, Jing Liu¹, Zixuan Xu¹

¹State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, China.

Investigative Ophthalmology & Visual Science

|January 2, 2024

Summary

Intermittent exotropia (IXT) patients show improved binocular function after surgery, as measured by the binocular summation ratio (BSR) using contrast sensitivity function (CSF). This novel BSR parameter aids in monitoring visual improvements in IXT.

More Related Videos

Assessing Binocular Central Visual Field and Binocular Eye Movements in a Dichoptic Viewing Condition

Assessing Binocular Central Visual Field and Binocular Eye Movements in a Dichoptic Viewing Condition

Published on: July 21, 2020

Quantification of Oculomotor Responses and Accommodation Through Instrumentation and Analysis Toolboxes

Quantification of Oculomotor Responses and Accommodation Through Instrumentation and Analysis Toolboxes

Published on: March 3, 2023

Related Experiment Videos

Last Updated: Jul 6, 2025

Comparison of Three Clinical Stereoscopic Methods for Measuring Binocular Visual Function During Amblyopic Treatment in Unilateral Amblyopia

Comparison of Three Clinical Stereoscopic Methods for Measuring Binocular Visual Function During Amblyopic Treatment in Unilateral Amblyopia

Published on: September 27, 2024

Assessing Binocular Central Visual Field and Binocular Eye Movements in a Dichoptic Viewing Condition

Assessing Binocular Central Visual Field and Binocular Eye Movements in a Dichoptic Viewing Condition

Published on: July 21, 2020

Quantification of Oculomotor Responses and Accommodation Through Instrumentation and Analysis Toolboxes

Quantification of Oculomotor Responses and Accommodation Through Instrumentation and Analysis Toolboxes

Published on: March 3, 2023

Area of Science:

Ophthalmology
Vision Science
Clinical Research

Background:

Intermittent exotropia (IXT) is the most prevalent form of strabismus.
Surgical intervention may enhance binocular function in individuals with IXT.

Purpose of the Study:

To assess binocular function in IXT patients pre- and post-surgery.
To evaluate the utility of the binocular summation ratio (BSR) derived from quantitative contrast sensitivity function (CSF) as a novel metric.

Main Methods:

A prospective study involving 63 IXT patients and 41 healthy controls.
Quantitative CSF testing was performed binocularly and monocularly to calculate BSR.
Forty-eight IXT patients underwent surgery, with assessments of BSR, stereoacuity, fusion, and questionnaires before and after the procedure.

Main Results:

IXT patients exhibited poorer baseline BSR compared to controls across various CSF metrics.
Post-surgery, significant improvements in BSR were observed in IXT patients.
Stereoacuity and fusion ability improved, correlating with enhanced BSR.

Conclusions:

The binocular summation ratio (BSR) effectively characterizes binocular function in IXT patients.
BSR serves as a valuable supplemental tool for monitoring binocularity in clinical settings.
Quantitative CSF-based BSR offers a novel approach to assessing visual function in strabismus.