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INDETERMINATE CELL HISTIOCYTOSIS WITH OCULAR INVOLVEMENT IN A NEONATE: A CASE REPORT
Alexis Kassotis1, Lauren Yeager, Dmitry Bogomolny
1Department of Ophthalmology, Edward S. Harkness Eye Institute, Columbia University Irving Medical Center, New York, New York.
Purpose:
The authors describe a case of Indeterminate cell histiocytosis, a rare disease of histiocytic proliferation on the spectrum of Langerhans cell histiocytosis.
Methods:
Data were collected through retrospective chart review.
Results:
The authors present a novel case of congenital Indeterminate cell histiocytosis with multisystem disease, including significant pan-ocular involvement. The neonate was successfully treated with the BRAF-kinase inhibitor dabrafenib, local anti-VEGF, and corticosteroid.
Conclusions:
The present case expands on the current ocular presentations of Indeterminate cell histiocytosis.
