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Updated: Jul 6, 2025

Pathological Analysis of Lung Metastasis Following Lateral Tail-Vein Injection of Tumor Cells

Pathological Analysis of Lung Metastasis Following Lateral Tail-Vein Injection of Tumor Cells

Published on: May 20, 2020

Anatomic Approach to Common and Uncommon Manifestations of Thoracic Leukemias with Radiologic-Pathologic Correlation.

Chi Wan Koo¹, Livia Maria Frota Lima¹, Allison Kerper¹

¹From the Department of Radiology (C.W.K., L.M.F.L.) and Department of Laboratory Medicine and Pathology (A.K., Y.C.L.), Mayo Clinic, 200 First St SW, Rochester, MN 55905.

Radiology. Cardiothoracic Imaging

|January 2, 2024

Summary

This summary is machine-generated.

This imaging essay focuses on direct intrathoracic manifestations of leukemia, excluding treatment effects. It details how leukemia infiltrates the lungs and other thoracic structures, impacting patients with hematologic malignancies.

Keywords:

Bone Marrow Hematologic Leukemia Pulmonary Soft Tissues/Skin Thorax

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Assessment of the Metabolic Profile of Primary Leukemia Cells

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Last Updated: Jul 6, 2025

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Published on: November 5, 2019

Assessment of the Metabolic Profile of Primary Leukemia Cells

Published on: November 21, 2018

Area of Science:

Hematology
Radiology
Oncology

Background:

Leukemias are hematopoietic malignancies originating in the bone marrow.
Clinical signs result from bone marrow suppression or leukemic organ infiltration.
Intrathoracic involvement is common, manifesting as lymphadenopathy or direct infiltration of thoracic structures.

Purpose of the Study:

To present an organ-based imaging depiction of direct, non-treatment-related intrathoracic findings in leukemia.
To correlate imaging findings with pathologic features of leukemic involvement.
To emphasize common and less common manifestations of leukemia within the thorax.

Main Methods:

Review of imaging findings in patients with leukemia.
Anatomic approach to image interpretation.
Correlation of imaging findings with pathological data.

Main Results:

Leukemic infiltration can affect the lungs, pleura, heart, bones, and soft tissues within the thorax.
Lymphadenopathy is a frequent direct manifestation.
Pulmonary abnormalities can include leukemic infiltration, distinct from treatment-related complications.

Conclusions:

Direct leukemic involvement of intrathoracic structures is a significant imaging finding.
Understanding these direct effects is crucial for accurate diagnosis and patient management.
Radiologists play a key role in identifying leukemic infiltration in the thorax.