Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

SNAREs and Membrane Fusion01:43

SNAREs and Membrane Fusion

10.9K
Once a transport vesicle has recognized its target organelle, the vesicular membrane needs to fuse with the target membrane to unload the cargo. Transmembrane proteins called SNAREs present on organelle membranes and their vesicles, mediate vesicle fusion.
SNAREs exist in pairs that symmetrically interact and catalyze the fusion of the lipid bilayers in vesicle and target organelle. v-SNARE in the vesicle membrane are single polypeptide chains that bind to a complementary t-SNARE, composed of 2...
10.9K
Fusion of Secretory Vesicles with the Plasma Membrane01:26

Fusion of Secretory Vesicles with the Plasma Membrane

11.1K
Proteins and neurotransmitters in secretory vesicles can be released from a cell upon vesicle docking, priming, and fusion with the plasma membrane. Vesicles are docked and primed in preparation for the quick exocytosis of their contents in response to a stimulus. The fusion process is mainly carried out by a SNAP Receptor or SNARE complex, consisting of synaptobrevin, syntaxin-1, and SNAP-25.
In 1993, Jim Rothman proposed that the antiparallel pairing of vesicular and transmembrane SNAREs, or...
11.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparative effects of aerobic exercise intensity strategies on cardiorespiratory fitness and cardiometabolic risk factors in overweight and obese postmenopausal women.

Physical activity and nutrition·2026
Same author

Development of a recombinase polymerase amplification-lateral flow assay for rapid visual detection of Meloidogyne hapla.

Archives of microbiology·2026
Same author

Complete mitochondrial genome sequence of Koelreuteria paniculata (Sapindaceae) and comparative analysis within the family Sapindaceae.

Scientific reports·2026
Same author

Viral Capsid Protein Architecture Informed Selection of ssDNA Aptamers for Specific Detection of FMDV.

Analytical chemistry·2026
Same author

Storage conditions and antiviral efficacy of yeast-derived vacuoles on T4 virus.

Microbiology spectrum·2026
Same author

Fabrication of immune-enhancing vesicles from reassembled yeast vacuolar membranes.

Colloids and surfaces. B, Biointerfaces·2025

Related Experiment Video

Updated: Jul 6, 2025

Combined Genetic and Chemical Capsid Modifications of Adenovirus-Based Gene Transfer Vectors for Shielding and Targeting
08:14

Combined Genetic and Chemical Capsid Modifications of Adenovirus-Based Gene Transfer Vectors for Shielding and Targeting

Published on: October 26, 2018

8.4K

Synergistic vesicle-vector systems for targeted delivery.

Christine Ardelle Marquez1, Cho-Im Oh1, Gna Ahn1,2

  • 1Department of Microbiology, Chungbuk National University, 1 Chungdae-Ro, Seowon-Gu, Cheongju, 28644, Republic of Korea.

Journal of Nanobiotechnology
|January 3, 2024
PubMed
Summary

Vesicle-vector systems (VVS) enhance drug delivery specificity using nanotechnology. This review explores VVS types, their synthesis, and future potential for targeted nanoscale drug delivery.

Keywords:
Drug delivery system (DDS)ExosomeExtracellular vesicle (EV)LiposomeTargeted deliveryVesicle-vector system (VVS)

More Related Videos

Delivery of Therapeutic siRNA to the CNS Using Cationic and Anionic Liposomes
10:33

Delivery of Therapeutic siRNA to the CNS Using Cationic and Anionic Liposomes

Published on: July 23, 2016

10.5K
Surface Functionalization of Hepatitis E Virus Nanoparticles Using Chemical Conjugation Methods
09:12

Surface Functionalization of Hepatitis E Virus Nanoparticles Using Chemical Conjugation Methods

Published on: May 11, 2018

6.9K

Related Experiment Videos

Last Updated: Jul 6, 2025

Combined Genetic and Chemical Capsid Modifications of Adenovirus-Based Gene Transfer Vectors for Shielding and Targeting
08:14

Combined Genetic and Chemical Capsid Modifications of Adenovirus-Based Gene Transfer Vectors for Shielding and Targeting

Published on: October 26, 2018

8.4K
Delivery of Therapeutic siRNA to the CNS Using Cationic and Anionic Liposomes
10:33

Delivery of Therapeutic siRNA to the CNS Using Cationic and Anionic Liposomes

Published on: July 23, 2016

10.5K
Surface Functionalization of Hepatitis E Virus Nanoparticles Using Chemical Conjugation Methods
09:12

Surface Functionalization of Hepatitis E Virus Nanoparticles Using Chemical Conjugation Methods

Published on: May 11, 2018

6.9K

Area of Science:

  • Nanotechnology
  • Biomedical Engineering
  • Pharmaceutics

Background:

  • Drug delivery systems (DDS) face challenges in achieving target specificity.
  • Nanotechnology advancements offer new solutions for precise drug delivery.
  • Lipid-based vesicles show promise as targeted drug carriers.

Purpose of the Study:

  • To review vesicle-vector systems (VVS) as a targeted drug delivery approach.
  • To discuss different VVS modification strategies and their properties.
  • To examine the applications, challenges, and future of VVS.

Main Methods:

  • Review of literature on vesicle-vector systems.
  • Categorization of VVS based on modification strategies: vesicle-probes, vesicle-vesicles, and genetically engineered vesicles.
  • Analysis of synthesis, properties, applications, and limitations of each VVS type.

Main Results:

  • Identified three main types of VVS based on modification strategies.
  • Highlighted synthesis methods and advantageous properties for targeted delivery.
  • Examined current applications, challenges, and limitations of VVS.

Conclusions:

  • Vesicle-vector systems offer high target specificity for nanoscale drug delivery.
  • Further research into VVS synthesis and engineering can overcome current limitations.
  • VVS hold significant future potential for advanced targeted therapeutics.