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Preparation of Mycobacterium Tuberculosis Culture Filtrate to Understand TB Pathogenesis
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Rv0687 a Putative Short-Chain Dehydrogenase is indispensable for pathogenesis of Mycobacterium tuberculosis

Gunapati Bhargavi, Mohan Krishna Mallakuntla, Deepa Kale

    Biorxiv : the Preprint Server for Biology
    |January 3, 2024
    PubMed
    Summary

    Rv0687, a short-chain dehydrogenases/reductases family gene, is crucial for Mycobacterium tuberculosis survival under stress and in host cells. Deleting Rv0687 impairs Mtb growth and increases host immune response, revealing its role in pathogenesis.

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