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Building a Multidisciplinary Care Pathway Supported by a Surgical Approach to Local Bone Formation.

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Osteoporosis affects millions, causing costly hip fractures. A new local osteo-enhancement procedure (LOEP) using a calcium-based implant shows promise for increasing bone mineral density and strength.

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Area of Science:

  • Orthopedics
  • Bone Metabolism
  • Biomaterials

Background:

  • Osteoporosis is a prevalent bone disease, particularly in Spain, affecting 3 million people, with high rates of fragility hip fractures.
  • The economic burden of osteoporosis in the EU is substantial, primarily due to fracture treatment costs.
  • Current treatment guidelines recommend a multidisciplinary approach, including local bone formation strategies.

Purpose of the Study:

  • To introduce and discuss a specific local osteo-enhancement procedure (LOEP) for osteoporosis treatment.
  • To present a clinical case utilizing the Ossure™ LOEP technique.
  • To explore patient selection criteria for this novel procedure.

Main Methods:

  • The Ossure™ LOEP technique involves percutaneous introduction of a calcium-based triphasic osteoconductive implant (AGN1) into the femoral neck and intertrochanteric region.
  • The procedure includes three steps: cavity preparation, cleaning, and filling with AGN1.
  • It can be performed under sedation with local anesthesia or spinal anesthesia.

Main Results:

  • The implant material (AGN1) has demonstrated an increase in bone mineral density (BMD) and proximal femoral strength.
  • The report details a clinical case study applying this technique.
  • Discussion focuses on identifying suitable candidates for the LOEP procedure.

Conclusions:

  • Local osteo-enhancement procedures (LOEP) are emerging as a viable treatment option for osteoporosis, as recognized by IOF and ESCEO guidelines.
  • The Ossure™ LOEP technique offers a minimally invasive approach to improve bone quality in critical hip regions.
  • Further investigation into patient selection will optimize the application of this bone-forming implant technology.