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COVID-19 mRNA Vaccination Trends Among Immunocompromised Patients
Bojan Lazarevic1, Allison R Casola1, Christopher V Chambers1
1From the Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA (BL); Department of Family and Community Medicine, Thomas Jefferson University, Philadelphia, PA (ARC, CVC).
Journal of the American Board of Family Medicine : JABFM
|January 3, 2024
Summary
COVID-19 vaccination trends in immunocompromised patients show that while most received 3+ mRNA doses, disparities exist, particularly between Black and White patients. Primary care should focus on patient-centered vaccine education to improve rates.
Area of Science:
- Immunology
- Public Health
- Epidemiology
Background:
- Immunocompromised individuals face higher risks of severe COVID-19.
- Assessing vaccination trends is crucial for public health strategies.
Purpose of the Study:
- To evaluate COVID-19 vaccination patterns among immunocompromised patients in an urban primary care setting.
- To identify trends in mRNA vaccine uptake within this vulnerable population.
Main Methods:
- Retrospective chart review of 887 immunocompromised patients from January 2021 to May 2022.
- Data collected included demographics, diagnoses, and COVID-19 mRNA vaccination status (doses and type).
- Descriptive statistics and paired t-tests were used for analysis.
Main Results:
- 62.7% of patients received 3 or more mRNA vaccine doses; 37.3% received 2 or fewer.
- Solid tumors (62.6%) and HIV/AIDS (23.8%) were common diagnoses.
- Significant disparities noted, with 42% of Black patients receiving 2 or fewer doses compared to White patients.
Conclusions:
- Despite high overall vaccination rates, significant racial disparities in COVID-19 vaccine uptake exist among immunocompromised patients.
- Primary care providers must enhance patient-centered education to address these disparities.
- Targeted outreach is essential to improve vaccination coverage in vulnerable populations.
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