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Caffeine Intoxication, in Which the Theophylline Level Served as an Indicator of the Treatment Course and the
Naoyuki Yoshimine1, Nobuyuki Oba1, Chika Hasegawa2
1Department of Gastroenterology, Tokyo Rosai Hospital, Japan Organization of Occupational Health and Safety, Japan.
Abstract:
A 51-year-old man presented with sudden-onset palpitations and dyspnea that had started 8 h earlier. The patient was restless and tachypneic and had persistent vomiting upon arrival. His sensorium and oxygen saturation levels rapidly declined three hours after arrival, and he was placed on a ventilator. On hospitalization day 2, he was removed from the ventilator and claimed that he had consumed a large amount of energy drinks (oral caffeine intake, approximately 1 g). The theophylline level on arrival had been elevated (9.0 μg/mL). Caffeine intoxication should be considered in patients presenting with restlessness, tachypnea, frequent vomiting, lactic acidosis, and electrolyte abnormalities.
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