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Treatment of psoriasis with dithranol cream compared with dithranol paste
Dermatologica
|January 1, 1986
Summary
Dithrocream and traditional dithranol showed similar effectiveness for psoriasis treatment. Dithrocream offered a better side effect profile, with less skin staining and irritation for patients.
Area of Science:
- Dermatology
- Pharmacology
Background:
- Psoriasis is a chronic inflammatory skin condition.
- Traditional treatments like dithranol in Lassar's paste are effective but can cause side effects.
Purpose of the Study:
- To compare the therapeutic effectiveness and side effect profiles of Dithrocream and dithranol in Lassar's paste for psoriasis.
Main Methods:
- A paired-comparison study was conducted.
- 15 hospitalized patients with psoriasis participated.
- Dithrocream was directly compared with dithranol in Lassar's paste.
Main Results:
- Both Dithrocream and dithranol in Lassar's paste demonstrated comparable therapeutic effectiveness in treating psoriasis.
- Dithrocream resulted in significantly fewer side effects, specifically reduced skin staining and irritation, compared to dithranol in Lassar's paste.
Conclusions:
- Dithrocream presents a viable alternative to dithranol in Lassar's paste for psoriasis management.
- Dithrocream offers an improved safety profile with reduced local side effects, enhancing patient tolerance and adherence.