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Updated: Jul 6, 2025

Author Spotlight: Exploring the Lifespan Dynamics of Healthy Human Hematopoiesis
Published on: December 8, 2023
Aggressive progressive pleuroparenchymal fibroelastosis developed long after allogenic hematopoietic stem cell
Osamu Imataki1, Makiko Uemura1
1Division of Hematology, Department of Internal Medicine, Faculty of Medicine Kagawa University Takamatsu Japan.
Abstract:
The typical pleuroparenchymal fibroelastosis (PPFE) after hematopoietic stem cell transplantation (HSCT) is characterized by late-onset progressive pulmonary complication within 5 years. PPFE shows a poor prognosis without definitive standard care other than lung transplantation. Our case indicated an over 20 years late-onset and aggressively exacerbating PPFE.
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