Synthesis and characterization of Anderson-Evans type polyoxometalates, antibacterial properties

In the present work, the new aluminium-substituted polyoxometalates of the Anderson-Evans type have been prepared and structurally defined by the reaction of aluminium (III) chloride hexahydrate and sodium tungstate dihydrate/sodium molybdate dihydrate in an aqueous basic medium. Elemental analysis, FT-IR, TGA, ¹H NMR, and ³¹P NMR analysis revealed that these polyoxometalates had the following formula: [Ph₄P]₃[Al(OH)₆Mo₆O₁₈]·4H₂O 1, [Ph₄P]₃[Al(OH)₆W₆O₁₈]·4H₂O 2, [C₇H₁₀N]₃[Al(OH)₆Mo₆O₁₈]·4H₂O 3, [C₇H₁₀N]₃[Al(OH)₆W₆O₁₈]·4H₂O 4. The compounds 1 and 2 show promising antibacterial activity against gram-positive Staphylcoccus aureus ATCC 25923 and gram-negative Escherichia coli ATCC 25922 bacteria.