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Updated: Jul 6, 2025

Formulation of Zinc-Based Nanomaterials using the Eucommia ulmoides Bark Extract and their Wound Healing Potential
Published on: December 27, 2024
Hemostatic and antibacterial calcium-copper zeolite gauze for infected wound healing
Mingtao Wang1, Wenzhao Zhang1, Chenchen Wang1
1Key Lab of Applied Chemistry of Zhejiang Province, Department of Chemistry, Zhejiang University Hangzhou 310027 China yulisha_bless@163.com jfan@zju.edu.cn lpxiao@zju.edu.cn.
Abstract:
The design and development of wound dressings with excellent procoagulant and antibacterial activity to achieve high wound healing effectiveness are highly desirable in clinical applications. In this work, we develop a calcium-copper zeolite gauze (CaCu-ZG) by a two-step process involving calcium and copper ion exchange in a zeolite gauze. The CaCu-ZG exhibits remarkable procoagulant and antibacterial abilities, as well as good biocompatibility. Compared with the medical gauze, the blood clotting time of CaCu-ZG significantly decreases and the antibacterial activity increases in both in vivo and in vitro experiments. The remarkable ability of wound healing has been verified using a mouse dorsal skin-infected wound model, demonstrating its great potential for wound treatment in clinical applications.
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