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Updated: Jul 6, 2025

Fabrication of Ti3C2 MXene Microelectrode Arrays for In Vivo Neural Recording
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Recent advances using MXenes in biomedical applications.

I-Chi Lee1, Yi-Chen Ethan Li2, James L Thomas3

  • 1Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Hsinchu, 300044, Taiwan.

Materials Horizons
|January 4, 2024
PubMed
Summary
This summary is machine-generated.

MXenes, novel 2D materials, show great promise in biomedicine. Their unique properties enable advanced applications in drug delivery, biosensing, and cancer therapy, driving innovation in healthcare.

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Area of Science:

  • Materials Science
  • Nanotechnology
  • Biomedical Engineering

Background:

  • MXenes are novel 2D transition metal carbides/nitrides (MXT) with excellent biocompatibility, conductivity, and photothermal properties.
  • These characteristics make MXenes highly suitable for diverse biomedical and biosensing applications.

Purpose of the Study:

  • To review recent advancements in MXene applications within biomedicine.
  • To highlight MXene's role in drug delivery, tissue engineering, antimicrobial activity, and biosensors.
  • To discuss MXene-based photothermal cancer therapy and multimodal treatments.

Main Methods:

  • Review of recent literature on MXene applications in drug delivery, tissue engineering, and biosensing.
  • Exploration of MXene utilization in photothermal cancer therapy and integrated treatments.
  • Analysis of MXene properties for controlled drug release and electrical stimulation.

Main Results:

  • MXenes facilitate controlled drug release via responses to pH, ROS, and electrical signals.
  • MXene's conductivity supports electrical stimulation for cells and photocatalytic antimicrobial applications.
  • MXene-based sensors (wearable, in situ) and photothermal cancer therapies show significant potential.

Conclusions:

  • MXenes offer remarkable properties for advanced biomedical applications, including drug delivery, biosensing, and cancer therapy.
  • Future development directions focus on overcoming challenges to further integrate MXenes into clinical practice.
  • The unique characteristics of MXenes position them for continued growth and innovation in the biomedical field.