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Comprehensive approach to controlling chronic hepatitis B in China
Shan Shan1, Xinyan Zhao1, Jidong Jia1
1Liver Research Center, Beijing Friendship Hospital, Capital Medical University, The National Clinical Research Center for Digestive Diseases, Beijing, China.
Clinical and Molecular Hepatology
|January 4, 2024
Summary
China
Area of Science:
- Public Health
- Epidemiology
- Infectious Diseases
Background:
- Hepatitis B virus (HBV) infection was highly endemic in China, with a 9.7% HBsAg prevalence in 1992.
- Comprehensive strategies have significantly reduced HBV transmission and childhood acquisition.
- Despite progress, challenges remain in diagnosis and treatment rates.
Purpose of the Study:
- To analyze the impact of vaccination and treatment policies on HBV prevalence in China.
- To identify persistent challenges in achieving HBV elimination goals.
- To propose a public health approach for HBV control.
Main Methods:
- Analysis of HBsAg prevalence data from 1992 to 2022.
- Review of clinical guidelines and drug pricing policies.
- Assessment of diagnosis and treatment rates.
- Evaluation of progress towards 2030 HBV-related mortality goals.
Main Results:
- HBsAg prevalence decreased to 5.6% in the general population and 0.1% in children under 5 by 2022.
- Improved vaccination coverage and antiviral drug accessibility have been achieved.
- Low diagnosis and treatment rates hinder the achievement of 2030 mortality reduction targets.
Conclusions:
- China has made substantial progress in controlling Hepatitis B virus infection through vaccination and improved treatment accessibility.
- A concerted public health approach is crucial to increase HBV testing and treatment uptake.
- Achieving the 2030 goal of eliminating viral hepatitis requires integrated efforts from all stakeholders.
