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The emerging role of ectodermal neural cortex 1 in cancer
Lingling He1, Chiyu Zhang2, Wenjing He3
1Department of Obstetrics, Jiangxi Provincial Maternal and Child Health Hospital, No. 318, Bayi Avenue, Nanchang, 330006, Jiangxi Province, China. 619148755@qq.com.
Scientific Reports
|January 4, 2024
Summary
Ectodermal neural cortex 1 (ENC1) protein is overexpressed in many cancers, promoting tumor growth and spread. Targeting ENC1 shows promise for cancer therapy by inhibiting cancer cell invasion and metastasis.
Area of Science:
- Molecular Biology
- Oncology
- Cell Biology
Background:
- Ectodermal neural cortex 1 (ENC1) regulates key cellular processes like proliferation, differentiation, and apoptosis.
- ENC1 overexpression is linked to poor prognosis in various cancers, including breast, lung, pancreatic, and colorectal cancer.
- ENC1 also influences neuronal development and neural crest cell differentiation.
Conclusions:
- ENC1 is a significant factor in cancer development and progression.
- Targeting ENC1 presents a promising therapeutic strategy for various cancers.
- Further research is needed to fully understand ENC1's complex role and optimize therapeutic interventions.
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