Related Experiment Video
Updated: Jul 6, 2025

Evaluation of Stem Cell Therapies in a Bilateral Patellar Tendon Injury Model in Rats
Published on: March 30, 2018
Stem cells and pain
Matheus Deroco Veloso da Silva1, Maiara Piva1, Geovana Martelossi-Cebinelli1
1Department of Pathology, Laboratory of Pain, Inflammation, Neuropathy and Cancer, State University of Londrina, Londrina 86057-970, Paraná, Brazil.
Stem cells (SCs) offer a promising alternative for pain relief due to their immune and neuromodulatory effects. SC therapies show potential for effective pain management with fewer side effects than traditional drugs.
Area of Science:
- Regenerative Medicine
- Neuroscience
- Immunology
Background:
- Current pain management options often have significant adverse events.
- There is a critical need for safer and more effective analgesic treatments.
- Stem cells (SCs) possess unique properties for therapeutic applications.
Purpose of the Study:
- To review the potential of stem cells (SCs) as an alternative treatment for pain.
- To explore the immune and neuromodulatory properties of SCs in pain management.
- To discuss the current state and future directions of SC-based analgesic therapies.
Main Methods:
- Review of existing scientific literature on stem cell therapy for pain.
- Analysis of the immunomodulatory and neuromodulatory mechanisms of SCs.
- Evaluation of clinical evidence and preclinical studies on SC-based pain relief.
Main Results:
- Stem cells demonstrate significant potential in managing various types of pain.
- SC therapies offer advantages such as multiple administration routes and dosages.
- Observed meaningful results with a low incidence of adverse effects.
Conclusions:
- Stem cell therapy presents a promising avenue for developing safer and more effective analgesics.
- Further research is essential to fully elucidate the mechanisms underlying SC-mediated pain relief.
- The field of SC-based pain management is rapidly evolving and requires continued investigation.
Related Concept Videos
Mesenchymal Stem Cells
Stem Cell Culture
Stem Cell Therapy for Tissue Regeneration
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
iPS Cell Differentiation
Induced Pluripotent Stem Cells
Somatic...
Source And Potency Of Stem Cells

