[Imaging after kidney transplantation in childhood and adolescence]

Doris Franke1, Diane Miriam Renz2, Hans-Joachim Mentzel3

  • 1Pädiatrische Sonographie, Klinik für Pädiatrische Nieren‑, Leber- und Stoffwechselerkrankungen, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland. franke.doris@mh-hannover.de.

PubMed

Insights

Ultrasound (US) is crucial for diagnosing complications in pediatric kidney disease and transplantation. Advanced US techniques and MRI offer comprehensive imaging, while excretory urography is outdated.

Area of Science:

  • Pediatric Nephrology
  • Medical Imaging
  • Transplant Surgery

Context:

  • Ultrasound (US) is the primary imaging modality for pediatric chronic kidney disease (CKD) and kidney transplantation.
  • It aids in assessing pre-transplant status and post-transplant acute and chronic phases.
  • Doppler sonography is key for identifying vascular and non-vascular complications.

Purpose:

  • To outline the role of various imaging modalities in pediatric kidney disease and transplantation.
  • To highlight the diagnostic capabilities of ultrasound, including Doppler, superb microvascular imaging (SMI), and contrast-enhanced ultrasonography (CEUS).
  • To discuss the utility of magnetic resonance imaging (MRI) techniques and the obsolescence of excretory urography.

Summary:

  • Ultrasound effectively diagnoses vascular (occlusions, thrombosis, stenosis) and non-vascular (dilatation, abscesses, leaks) complications in pediatric kidney patients.
  • While US signs of acute rejection are suggestive, kidney biopsy remains the gold standard; US helps rule out other causes.
  • Multimodal US techniques and MRI (DWI, MRA, MRU) enhance diagnostic accuracy for transplant assessment and planning.

Impact:

  • Optimizes the diagnosis and management of pediatric kidney disease and post-transplant complications.
  • Provides cost-effective and rapid diagnostic solutions for vascular and non-vascular issues.
  • Guides surgical planning and long-term assessment in pediatric kidney transplant recipients.