Related Experiment Video
Updated: Jul 6, 2025

Author Spotlight: Developing a Bedside Protocol for Kidney and Genitourinary Ultrasonography
Published on: June 21, 2024
[Imaging after kidney transplantation in childhood and adolescence]
Doris Franke1, Diane Miriam Renz2, Hans-Joachim Mentzel3
1Pädiatrische Sonographie, Klinik für Pädiatrische Nieren‑, Leber- und Stoffwechselerkrankungen, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland. franke.doris@mh-hannover.de.
Insights
Ultrasound (US) is crucial for diagnosing complications in pediatric kidney disease and transplantation. Advanced US techniques and MRI offer comprehensive imaging, while excretory urography is outdated.
Area of Science:
- Pediatric Nephrology
- Medical Imaging
- Transplant Surgery
Context:
- Ultrasound (US) is the primary imaging modality for pediatric chronic kidney disease (CKD) and kidney transplantation.
- It aids in assessing pre-transplant status and post-transplant acute and chronic phases.
- Doppler sonography is key for identifying vascular and non-vascular complications.
Purpose:
- To outline the role of various imaging modalities in pediatric kidney disease and transplantation.
- To highlight the diagnostic capabilities of ultrasound, including Doppler, superb microvascular imaging (SMI), and contrast-enhanced ultrasonography (CEUS).
- To discuss the utility of magnetic resonance imaging (MRI) techniques and the obsolescence of excretory urography.
Summary:
- Ultrasound effectively diagnoses vascular (occlusions, thrombosis, stenosis) and non-vascular (dilatation, abscesses, leaks) complications in pediatric kidney patients.
- While US signs of acute rejection are suggestive, kidney biopsy remains the gold standard; US helps rule out other causes.
- Multimodal US techniques and MRI (DWI, MRA, MRU) enhance diagnostic accuracy for transplant assessment and planning.
Impact:
- Optimizes the diagnosis and management of pediatric kidney disease and post-transplant complications.
- Provides cost-effective and rapid diagnostic solutions for vascular and non-vascular issues.
- Guides surgical planning and long-term assessment in pediatric kidney transplant recipients.
Abstract:
The ultrasound (US) examination is the most important imaging procedure in the clinical care of children with chronic kidney disease, the assessment before kidney transplantation and in the acute and chronic phase after successful kidney transplantation. In trained hands, particularly with experience in Doppler sonography, US ensures that vascular complications, such as occlusions, thrombosis, stenosis as well as non-vascular complications, e.g., urinary tract dilatation, abscesses, hematomas, urine leaks or lymphoceles, are cost-effectively and rapidly diagnosed at any time. For the diagnosis of acute rejection, the US signs in the intraindividual course are only suggestive, but not specific. The gold standard for the diagnosis of acute rejection is a kidney biopsy. In these cases, US serves to exclude other causes. The use of multimodal techniques, various Doppler techniques and microvascular procedures, such as superb microvascular imaging (SMI) or B‑flow and contrast-enhanced ultrasonography (CEUS), optimizes the imaging in the context of transplantations in children. Magnetic resonance imaging with diffusion-weighed imaging (DWI), magnetic resonance angiography (MRA) and magnetic resonance urography (MRU) as well as functional MRU (fMRU) performed with the administration of gadolinium-containing contrast agents, are part of the extended diagnostics and possibly necessary for surgical planning in the early phase after kidney transplantation and for long-term assessment after transplantation. Excretory urography is associated with ionizing radiation and intravenous administration of iodine-containing contrast medium and is obsolete in children. Computed tomography (CT) using age-adapted and weight-adapted dose protocols is an alternative in emergencies if MRI is not available.
Related Concept Videos
Radiological Investigation I: X-ray and CT
Imaging Studies for Cardiovascular System III: X-Ray
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...

