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Chromosome Preparation From Cultured Cells
Published on: January 28, 2014
Cytogenetic studies on B-cell leukemias of AKR origin
International Journal of Cancer
|March 15, 1987
Abstract:
The karyotype of B-cell leukemias of AKR origin was studied by G-banding. In contrast to previous observations indicating trisomy of chromosome 15 in spontaneous and chemically-induced B-cell leukemias, 11 out of 15 tumors analyzed had normal diploid karyotypes. Four tumors with the modal number 39-41 had different chromosome markers specific for each tumor. The possible correlation between non-random chromosomal changes and the target cell involved in the initial transformation in AKR leukemogenesis is discussed.
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