Related Experiment Video
Updated: Jul 6, 2025

08:03
Spontaneous and Evoked Measures of Pain in Murine Models of Monoarticular Knee Pain
Published on: February 22, 2019
8.5K
Differences in Pain Experience Among Different Racial and Ethnic Groups.
Elizabeth Lane1, Chris Barnes2, Julie M Fritz3
1Department of Physical Therapy & Athletic Training, University of Utah, Salt Lake City, Utah, USA.
Physical Therapy
|January 5, 2024
Summary
Race influences how pain catastrophizing and self-efficacy affect pain intensity in individuals with chronic spinal pain. These psychological factors have differential impacts based on race, impacting pain management strategies.
Area of Science:
- Pain Management
- Health Disparities
- Psychology of Pain
Background:
- Race-based disparities in pain management persist.
- Understanding mediating and moderating factors is crucial for equitable care.
- Chronic spinal pain affects diverse populations undergoing physical therapy.
Purpose of the Study:
- To investigate pain catastrophizing and self-efficacy as mediators of race-based differences in pain intensity.
- To examine the moderating role of race on the relationship between pain catastrophizing/self-efficacy and pain outcomes.
- To inform targeted interventions for chronic spinal pain patients.
Main Methods:
- Secondary analysis of a cluster-randomized trial involving 274 participants with chronic spinal pain.
- Mediation analyses assessed the role of pain catastrophizing and self-efficacy in race-pain intensity associations.
- Moderation analyses used multiple linear regression to evaluate race's role in pain outcome relationships.
Main Results:
- Black participants reported higher baseline pain intensity compared to non-Hispanic White participants.
- Both pain catastrophizing and self-efficacy mediated the relationship between race and baseline pain intensity.
- Race moderated the association between pain catastrophizing/self-efficacy and 12-week pain intensity.
Conclusions:
- Pain catastrophizing and self-efficacy have distinct effects on pain intensity that vary by race.
- These findings highlight the need to consider race in pain management strategies.
- Addressing race-related differences in pain perception can help reduce health disparities.
Related Concept Videos
Stereotypes, Prejudice, and Discrimination
90.2K
Humans are very diverse and although we share many similarities, we also have many differences. The social groups we belong to help form our identities (Tajfel, 1974). These differences may be difficult for some people to reconcile, which may lead to prejudice toward people who are different. Prejudice is a negative attitude and feeling toward an individual based solely on one’s membership in a particular social group (Allport, 1954; Brown, 2010). Prejudice is common against people who...
90.2K
Pain
481
Pain serves as a critical warning signal that alerts the body to potential or actual harm. When mechanical pressure on the skin is intense, such as from a sharp pinch, the sensation transitions from touch to pain. Similarly, extreme temperatures, like a hot pot handle, convert the sensation of heat into pain. Pain can also result from overstimulation of other senses, such as blinding light, loud noise, or the intense heat from habañero peppers. This ability to sense pain is essential for...
481
Analgesia and Pain Management
625
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
625
Local Anesthetics: Differential Sensitivity of Nerve Fibers
838
Local anesthetics (LAs) block the sodium channels of nerve trunks, sensory nerve endings, and neuromuscular junctions. Although LAs can block all kinds of nerves, the sensitivity of nerve fibers differs according to nerve types and structures. LAs are known to block myelinated fibers faster than unmyelinated ones. Also, they block pain or sensory neurons at low concentrations without affecting the motor neurons involved in muscle contractions. This helps relieve labor pain without affecting the...
838
Surveys
14.8K
Often, psychologists develop surveys as a means of gathering data. Surveys are lists of questions to be answered by research participants, and can be delivered as paper-and-pencil questionnaires, administered electronically, or conducted verbally. Generally, the survey itself can be completed in a short time, and the ease of administering a survey makes it easy to collect data from a large number of people.
14.8K
Nociception
27.9K
Nociception—the ability to feel pain—is essential for an organism’s survival and overall well-being. Noxious stimuli such as piercing pain from a sharp object, heat from an open flame, or contact with corrosive chemicals are first detected by sensory receptors, called nociceptors, located on nerve endings. Nociceptors express ion channels that convert noxious stimuli into electrical signals. When these signals reach the brain via sensory neurons, they are perceived as pain.
27.9K

