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Acute effects of pirenzepin on bronchospasm
International Journal of Clinical Pharmacology, Therapy, and Toxicology
|December 1, 1986
Abstract:
The response to pirenzepin, a new acetylcholine receptor blocking agent, was assessed and compared to placebo in patients with reversible bronchoconstriction. A single intravenous injection of 20 mg of pirenzepin induced a significant reduction of airway resistance compared to placebo (p less than 0.05). The anticholinergic substance pirenzepin appears to be useful in the treatment of bronchospasm.