Adaptive metabolic response to short-term intensive fasting

Suping Zhang1, Yaqi Lv2, Jiawei Qian2

  • 1Research Center for Blood Engineering and Manufacturing, Cyrus Tang Medical Institute, National Clinical Research Center for Hematologic Diseases, Collaborative Innovation Center of Hematology, Jiangsu Institute of Hematology, State Key Laboratory of Radiation Medicine and Protection, Soochow University, Suzhou 215123, China; Suzhou Center for Disease Control and Prevention, Suzhou 215004, China.

Summary

Short-term intensive fasting (STIF) triggers adaptive metabolic responses in the liver and kidney. The body upregulates catabolic enzymes to manage metabolite accumulation, demonstrating a protective mechanism against fasting stress.

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