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Murine Kidney Transplant Technique
Published on: October 20, 2015
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Clot stones in transplant kidneys
Mon Mon Oo1, Silvia Proietti2, Franco Gaboardi2
1Urology, San Raffaele Hospital, Milano, Lombardia, Italy urommoo@gmail.com.
BMJ Case Reports
|January 5, 2024
Summary
Two cases of transplanted kidney stones formed from blood clots were identified. These unusual kidney stones, characterized by a dense outer shell and lucent center, were successfully removed via percutaneous nephrolithotomy.
Area of Science:
- Nephrology
- Urology
- Radiology
Background:
- Renal transplantation is a life-saving procedure for end-stage renal disease.
- Kidney stones can be a complication after renal transplantation.
- Unusual stone presentations require careful diagnostic consideration.
Observation:
- Two patients with transplanted kidneys presented with gross hematuria years after their procedures.
- Computed tomography (CT) revealed unique kidney stones with a hyperdense outer shell (Hounsfield units >500) and a radiolucent center (HU <100).
Findings:
- The stones were successfully treated with percutaneous nephrolithotomy.
- Analysis confirmed the outer layer was calcium oxalate monohydrate.
- The inner portion of the stone in one case consisted of organized blood clot material, indicating clot lithogenesis.
Implications:
- Clinicians should consider clot lithogenesis in patients with hematuria and kidney stones, particularly in allograft kidneys.
- Awareness of these unusual radiological characteristics aids in diagnosis and management.
- Prompt investigation following hematuria can identify and treat such stones effectively.
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