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Published on: November 6, 2019
Perioperative clinical practice recommendations for pediatric tonsillectomy: a systematic review
Alfonso E Albornoz1,2, Mehwish Rana3, Jason Hayes1,2
1Department of Anesthesia and Pain Medicine, The Hospital for Sick Children, Toronto, ON, Canada.
Insights
This systematic review analyzed clinical practice guidelines for pediatric tonsillectomy perioperative care. Acetaminophen, NSAIDs, and steroids are recommended for pain management in children undergoing tonsillectomy.
Area of Science:
- Pediatric Surgery
- Anesthesiology
- Evidence-Based Medicine
Background:
- Tonsillectomy is a common pediatric surgical procedure.
- Existing clinical practice guidelines (CPGs) primarily focus on surgical decisions, not perioperative management.
- There is a need for CPGs specifically addressing the perioperative care of children undergoing tonsillectomy.
Approach:
- A systematic review was conducted to identify and analyze existing CPGs for pediatric tonsillectomy perioperative management.
- Searches were performed in Embase, MEDLINE, MEDLINE ePub Ahead of Print, and CINAHL up to August 3, 2022.
- Inclusion criteria focused on CPGs with evidence-based recommendations for tonsillectomy under general anesthesia in children, published in English after 2000.
Key Points:
- Five eligible CPGs were identified; two were rated high quality.
- Most recommendations focused on pain management, with acetaminophen being universally recommended.
- Nonsteroidal anti-inflammatory drugs (NSAIDs) and steroids were supported as adjuncts in most CPGs.
Conclusions:
- Acetaminophen, NSAIDs, and steroids are recommended for perioperative management of pediatric tonsillectomy.
- Future CPGs should address safe opioid use, considering obstructive sleep apnea severity and opioid-sparing techniques.
- Further clarification is needed on adjuncts like dexmedetomidine, high-dose dexamethasone, and gabapentinoids.
Purpose:
Tonsillectomy is one of the most common surgical procedures performed in children. Since most clinical practice guidelines (CPGs) are designed to support surgical decisions, none are specifically designed for the perioperative management of children undergoing tonsillectomy. We aimed to identify and analyze the existing CPGs with recommendations for the perioperative management of children undergoing tonsillectomy by conducting a systematic review.
Source:
We searched Embase, MEDLINE, MEDLINE ePub Ahead of Print, and CINAHL for relevant articles published from inception to 3 August 2022. The inclusion criteria were: 1) CPG of perioperative recommendations for tonsillectomy under general anesthesia in children, 2) CPG that include at least one evidence-based recommendation, 3) peer-reviewed CPG published in English after 2000. We extracted data on baseline characteristics of each CPG and general recommendations for perioperative interventions or complications.
Principal Findings:
Out of five eligible CPGs, AGREE II and REX confirmed that two CPGs were high quality while only one of the two was recommended for implementation without modifications. Most of the recommendations were for pain management. Acetaminophen was the only medication recommended in all five CPG. Except for the oldest CPG, the CPG all supported of the use of nonsteroidal anti-inflammatory drugs and steroids as a pain adjunct.
Conclusions:
Acetaminophen, nonsteroidal anti-inflammatory drugs, and steroids are recommended in the perioperative management of pediatric tonsillectomy. Future CPG should further clarify the safe use of opioids based on severity of obstructive sleep apnea and in the context of opioid-sparing techniques, such as dexmedetomidine, high-dose dexamethasone, and gabapentinoids.
Study Registration:
PROSPERO (CRD42021253374); first submitted 18 June 2021.
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