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Danish value sets for the EORTC QLU-C10D utility instrument.

Jens Lehmann1,2, Leslye Rojas-Concha3, Morten Aagaard Petersen3

  • 1University Hospital of Psychiatry II, Medical University of Innsbruck, Anichstraße 36, 6020, Innsbruck, Austria. jens.lehmann@i-med.ac.at.

Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation
|January 6, 2024
PubMed
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Correction: Needs and health-related quality of life domains relevant to people in Europe with advanced cancer in need of palliative care: a systematic review of qualitative research.

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Health-related quality of life domains relevant to people in Europe undergoing cancer treatment: a systematic review of qualitative research.

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This study developed Danish utility weights for the European Organisation for Research and Treatment of Cancer Quality of Life Utility Cancer (EORTC QLU-C10D) instrument. These weights are crucial for cost-utility analyses in Danish cancer patients.

Area of Science:

  • Health Economics
  • Psychometrics
  • Cancer Research

Background:

  • The European Organisation for Research and Treatment of Cancer Quality of Life Utility Cancer (EORTC QLU-C10D) is a cancer-specific utility instrument.
  • Country-specific utility weights are essential for accurate cost-utility analyses and health technology assessment.

Purpose of the Study:

  • To develop Danish utility weights for the EORTC QLU-C10D instrument.
  • To provide data for cost-utility analyses in Danish cancer patients.
  • To enable comparisons with other country-specific utility data.

Main Methods:

  • A standardized methodology was employed with 1001 adult participants from the Danish general population.
  • A cross-sectional web-based survey and discrete choice experiment (DCE) were conducted.
Keywords:
CancerDenmarkDiscrete choice experimentEORTC QLQ-C30Quality of lifeUtility

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  • Utility weights were calculated using conditional logistic regression with correction for non-monotonicity.

    • Main Results:

    • The sample was representative of the Danish general population regarding age and gender.
    • Physical functioning, pain, and role functioning demonstrated the largest utility decrements.
    • Lack of appetite, sleep disorders, and fatigue showed the smallest utility decrements.

    Conclusions:

    • The EORTC QLU-C10D is a promising measure for health technology assessment in cancer care.
    • The developed Danish utility weights are valuable for cost-utility analyses in Denmark.
    • This study contributes essential country-specific data for international comparisons.