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Updated: Jul 6, 2025

Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
Published on: April 22, 2019
The Next Chapter in Immunotherapy and Radiation Combination Therapy: Cancer-Specific Perspectives
Amy J Wisdom1, Christopher A Barker2, Joe Y Chang3
1Harvard Radiation Oncology Program, Boston, Massachusetts.
Abstract:
Immunotherapeutic agents have revolutionized cancer treatment over the past decade. However, most patients fail to respond to immunotherapy alone. A growing body of preclinical studies highlights the potential for synergy between radiation therapy and immunotherapy, but the outcomes of clinical studies have been mixed. This review summarizes the current state of immunotherapy and radiation combination therapy across cancers, highlighting existing challenges and promising areas for future investigation.
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