Related Experiment Video
Updated: Jul 6, 2025
Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia
Published on: September 18, 2013
Delayed diagnosis of advanced stage Leukemia in Two Pediatric Patients with Oral Manifestation
1Department of Pedodontics and Preventive Dentistry, Institute of Dental Sciences, Bareilly, Uttar Pradesh, India.
Background:
Leukemia is a disease in which hematopoietic stem cell mutation leads to the uncontrolled growth of immature blood cells. These abnormal cells, which displace healthy cells, are the reason for the bone marrow's failure and demise.
Objective:
To report unnoticed cases of delayed Leukemia in two patients.
Case Report:
A 9-year-old male and 14-year-old female born to a non-consanguineous marriage presented with oral manifestations after getting dental treatment in their native place. Acute Leukemia was suspected based on their total blood count.
Conclusions:
Understanding the unusual symptoms and signs of acute Leukemia aids in early identification and effective patient care. Key words:Hematologic Neoplasms, Classification, Incidence, Diagnosis, Child, Young Adult.
Related Concept Videos
01:22Bone Marrow Sampling and Transplants
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
02:50Combination Therapies and Personalized Medicine
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
02:07Tumor Progression
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...