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Updated: Jul 6, 2025

Tracking Drug-induced Changes in Receptor Post-internalization Trafficking by Colocalizational Analysis
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TrackChain: Hyperledger based pharmaceutical supply chain - Resource utilization perspective.

C M Naga Sudha1, Jesu Vedha Nayahi J2

  • 1Department of Computer Technology, Anna University - MIT Campus, Chennai, Tamilnadu, India.

Heliyon
|January 8, 2024
PubMed
Summary
This summary is machine-generated.

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Blockchain technology enhances pharmaceutical supply chain security and transparency. Hyperledger Sawtooth offers superior resource utilization and increased transaction capacity compared to Hyperledger Fabric.

Area of Science:

  • Computer Science
  • Supply Chain Management
  • Information Technology

Background:

  • Blockchain technology offers a decentralized and distributed ledger system for secure peer-to-peer transactions.
  • Supply chains benefit from enhanced security, accessibility, and inventory management through blockchain integration.
  • Logistical challenges in supply chains include data access and quality assurance, which blockchain can address.

Purpose of the Study:

  • To explore the application of blockchain in pharmaceutical supply chains for improved traceability and security.
  • To compare the performance of Hyperledger Fabric and Hyperledger Sawtooth platforms for supply chain solutions.
  • To evaluate the resource utilization and transaction efficiency of different blockchain frameworks.

Main Methods:

Keywords:
Hyperledger fabricHyperledger sawtoothPharmaceutical drugsResource consumptionSupply chain

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  • Development of a decentralized supply chain concept on two platforms: Hyperledger Fabric and Hyperledger Sawtooth.
  • Comparative analysis of Hyperledger Sawtooth and Hyperledger Fabric concerning resource utilization (CPU consumption).
  • Assessment of Hyperledger Sawtooth's suitability for decentralized applications with separated business logic.

    • Main Results:

    • Hyperledger Sawtooth demonstrated lower CPU consumption compared to Hyperledger Fabric.
    • The separation of application domain from the core system in Sawtooth simplifies development and maintenance.
    • Lower resource utilization in Sawtooth facilitates an increased number of transactions.

    Conclusions:

    • Hyperledger Sawtooth is well-suited for developing decentralized applications in supply chain management due to its resource efficiency.
    • Blockchain integration, particularly with Hyperledger Sawtooth, significantly improves pharmaceutical supply chain traceability, security, and operational efficiency.
    • The findings suggest Hyperledger Sawtooth as a preferred framework for enhancing supply chain performance through increased transaction throughput.