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Updated: Jul 6, 2025
Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
Exercise-induced vasospastic angina diagnosed with a hand grip test in the catheterization laboratory: a case report
Yoshiaki Kawase1, Takayuki Warisawa1,2,3, Kento Kikuchi1
1Department of Cardiology, Gifu Heart Center, 4-14-4 Yabutaminami, Gifu 500-8384, Japan.
Background:
Exercise-induced vasospastic angina (VSA) is a relatively uncommon clinical scenario and is difficult to diagnose in the catheterization laboratory.
Case Summary:
A 61-year-old Japanese man presented to our hospital with complaints of angina upon exertion in the morning. Neither a 12-lead electrocardiogram nor an echocardiogram showed any abnormal findings. Invasive coronary angiogram revealed moderate stenosis in the left anterior descending coronary artery. A hand grip test was performed, during which the patient experienced chest pain, and coronary angiogram showed coronary spasm at the site of organic stenosis with delayed coronary flow. Intracoronary nitrates (300 ug) were administered, resulting in the release of coronary spasm.
Conclusion:
The hand grip test may serve as a useful method for diagnosing exercise-induced VSA in the catheterization laboratory.
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