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Intraperitoneal hyaline vascular Castleman disease: Three case reports
Jia-Wei Gao1, Zhe-Yi Shi1, Zhao-Bi Zhu1
1Department of General Surgery, The Second Affiliated Hospital of Soochow University, Suzhou 215004, Jiangsu Province, China.
World Journal of Clinical Cases
|January 8, 2024
Summary
Castleman disease (CD) is a rare lymphoproliferative disorder with varied symptoms, making diagnosis challenging. Accurate diagnosis, often relying on pathology, is crucial for appropriate treatment of this complex condition.
Area of Science:
- Oncology
- Pathology
Background:
- Castleman disease (CD) is a rare, non-malignant lymphoproliferative disorder with an unclear cause.
- Varied clinical presentations complicate the diagnosis and treatment of CD.
Observation:
- This report reviews three cases of intraperitoneal Castleman disease diagnosed between January 2018 and June 2023.
- Patients underwent clinical, paraclinical, histopathological, and immunohistochemical examinations.
Findings:
- All three patients were definitively diagnosed with Castleman disease.
- Diagnosis relied on routine histopathological and immunohistochemical findings due to a lack of specific symptoms or lab abnormalities.
Implications:
- Castleman disease is a complex and rare entity requiring precise diagnosis.
- Histopathological and immunohistochemical analyses are essential for diagnosing CD.
- Accurate diagnosis is key to selecting effective treatment strategies for patients with Castleman disease.
