Related Experiment Video

Updated: Jul 6, 2025

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
06:29

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques

Published on: June 11, 2019

10.4K

Recurrent left ventricular thrombus due to essential thrombocythemia complicated by COVID-19

Kenta Matsui1, Tadashi Kitamura1, Shinzo Torii1

  • 1Department of Cardiovascular Surgery, Kitasato University School of Medicine, Sagamihara, Japan.

Journal of Cardiology Cases
|January 8, 2024
PubMed

Insights

Essential thrombocythemia and COVID-19 increase thrombosis risk, especially during cardiac surgery. This case highlights aggressive blood-thinning therapy to prevent recurrent left ventricular thrombus after surgery.

Area of Science:

  • Cardiology
  • Hematology
  • Infectious Diseases

Background:

  • Essential thrombocythemia (ET) is a myeloproliferative neoplasm increasing thrombosis risk.
  • Cardiac surgery perioperative periods elevate risks for thrombosis and hemorrhage.
  • Coronavirus disease 2019 (COVID-19) is independently associated with thrombotic complications.

Observation:

  • A 69-year-old male with ET and COVID-19 developed a left ventricular thrombus (LVT).
  • Initial thrombectomy was followed by recurrent LVT eight days post-surgery.
  • Cardiac tamponade occurred after a second thrombectomy, necessitating surgical drainage.

Findings:

  • Aggressive multimodal blood-thinning therapy, including anticoagulation and antiplatelet agents, was initiated after the second thrombectomy.
  • The patient recovered and was discharged 25 days after the second surgery without complications.
  • This case suggests a potential benefit of aggressive blood-thinning strategies in managing complex LVT in high-risk patients.

Implications:

  • Managing LVT in patients with concurrent ET and COVID-19 requires careful consideration of thrombotic and hemorrhagic risks.
  • Aggressive anticoagulation and antiplatelet therapy may be crucial in preventing recurrent thrombosis in such complex cases.
  • This case underscores the importance of individualized treatment strategies for patients with multiple cardiovascular and hematological risk factors.

Keywords:
COVID-19Essential thrombocythemiaLeft ventricular thrombus

More Related Videos

Implantation of Total Artificial Heart in Congenital Heart Disease07:27

Implantation of Total Artificial Heart in Congenital Heart Disease

Published on: July 18, 2014

24.7K
Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia08:05

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia

Published on: December 19, 2020

14.2K

Related Concept Videos

Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
227
Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.01:25

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
2.8K
Pulmonary Hypertension: Classification and Pathogenesis01:30

Pulmonary Hypertension: Classification and Pathogenesis

Pulmonary hypertension (PH) is a severe health condition in which the mean pulmonary arterial pressure increases to 25 mmHg or more, even when the body is at rest. This high pressure in the blood vessels that transport blood from the heart to the lungs can cause various symptoms, including shortness of breath, can lead to right heart failure, and significantly affect the overall quality of life.
There are various classifications for PH, each relating to different underlying causes and also...
180
COPD: Pathogenesis and Clinical Features01:20

COPD: Pathogenesis and Clinical Features

Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
275
Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
2.8K
Ischemic Heart Disease: Overview01:17

Ischemic Heart Disease: Overview

Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
1.3K