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Fungal keratitis after amniotic membrane placement.

Lena Chen¹, Deena Dahshan¹, Thomas Mauger¹

¹West Virginia University Department of Ophthalmology, Morgantown, WV, USA.

American Journal of Ophthalmology Case Reports

|January 8, 2024

Summary

Fungal keratitis, including rare Sistotrema biggsiae, can occur days after amniotic membrane transplantation (AMT). Early recognition and management are crucial for preventing severe vision loss in patients undergoing AMT.

Keywords:

Amniotic membrane Fungal Fusarium Keratitis Sistotrema

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Area of Science:

Ophthalmology
Microbiology
Transplantation

Background:

Amniotic membrane transplantation (AMT) is a common procedure for corneal healing.
Fungal keratitis is a rare but serious complication following AMT.

Observation:

Two cases of fungal keratitis post-AMT are presented: Fusarium and Sistotrema biggsiae.
One patient required extensive treatment for Fusarium keratitis, while the other improved with topical therapy for S. biggsiae.

Findings:

This is the first reported case of Sistotrema biggsiae keratitis in humans.
Fungal keratitis can present within 10 days of AMT, a previously unreported timeframe.

Implications:

Highlights the risk of severe microbial keratitis after AMT, emphasizing prompt diagnosis.
Underscores the importance of considering unusual fungal pathogens and close patient monitoring post-AMT, especially in monocular patients.