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Published on: June 10, 2013
Opioid prescription patterns in a children's hospital from 2012 to 2016
Nicole Titze1, Rishi Bhargava2, Ara Jamasbi Montalvo3
1Department of Emergency Medicine, Harbor-UCLA Medical Center, Torrence, California.
Insights
Pediatric opioid prescriptions decreased significantly from 2012 to 2016. Increased age and longer hospital stays were linked to more pain medication prescriptions, highlighting evolving pediatric pain management strategies.
Area of Science:
- Pediatric pharmacology
- Pain management
- Public health
Background:
- The opioid epidemic has increased opioid use in adults.
- Pediatric pain management requires careful consideration due to potential risks.
- Understanding trends in pediatric analgesic prescribing is crucial.
Purpose of the Study:
- To analyze trends in narcotic and non-narcotic pain medication prescriptions in pediatric patients.
- To identify changes in pediatric pain management over time.
- To examine factors associated with opioid prescription in children and adolescents.
Main Methods:
- Analysis of 58,402 analgesic prescriptions for patients aged 0-21 years (May 2012-November 2016).
- Logistic regression model to assess the association of age, sex, diagnosis, and hospital stay length with opioid prescription probability.
- Retrospective review of prescription data from a large pediatric hospital.
Main Results:
- A statistically significant reduction in opioid prescriptions was observed from 2012 to 2016 (p < 0.001).
- Increased age and longer hospital stays were directly associated with higher probabilities of opioid prescription (p < 0.001).
- Demographic shifts noted, with a male predominance in younger patients (<15 years) and a female predominance in older adolescents (>16 years).
Conclusions:
- Overall opioid prescriptions decreased in pediatric patients, potentially due to FDA regulations and increased awareness of opioid-related harms.
- Age and length of hospital stay are significant factors influencing analgesic prescribing patterns.
- Further research is warranted to explore specific opioid prescription patterns within the pediatric population.
Study Objective:
Pain management is a widely discussed topic, especially in the setting of the current opioid epidemic. Previous studies have shown that the use of opioids increased in the adult population. We aimed to look at the use of narcotic and non-narcotic pain medications at a large pediatric hospital to discern if patterns of pediatric pain management changed over time.
Methods:
58,402 analgesic prescriptions of patients 0-21 years of age were analyzed from May 2012 to November 2016. A logistic regression model was fitted to examine the association of age, sex, primary diagnosis, and the length of hospital stay with probability of opioid prescription.
Results:
36,560 patients aged 0-21 years (mean: 10.5, median: 11.0, and standard deviation (SD): 7.42) received analgesic pain medications. 21,847 (59.8 percent) patients were prescribed more than one analgesic. There was a male predominance in patients <15 years of age; however, in adolescents >16 years, females constituted 57.1 percent of patients. Data also showed a statistically significant reduction of opioid prescriptions from 2012 to 2016 (p < 0.001). Age and length of hospital stay were directly associated with opioid prescription (p < 0.001).
Conclusion:
Data show that there is a decrease in overall opioid prescriptions among pediatric patients, which may be secondary to new Food and Drug Administration regulations and increased awareness of morbidity associated with opioid use. Not surprisingly, increased hospital stay and increase in age lead to more analgesic prescriptions. Further investigation is needed to determine the differences within opioid prescription patterns.
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