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A Detailed Protocol for Perspiration Monitoring Using a Novel, Small, Wireless Device
Published on: November 24, 2016
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Stretchable and Smart Wettable Sensing Patch with Guided Liquid Flow for Multiplexed in Situ Perspiration Analysis.
Yuping Sun1,2, Jianhui Wang1,2, Qianying Lu1,2
1College of Engineering and Applied Sciences, National Laboratory of Solid State Microstructure, and Collaborative Innovation Center of Advanced Microstructures, Nanjing University, Nanjing 210093, China.
ACS Nano
|January 8, 2024
Summary
A new stretchable, smart wettable patch offers affordable, noninvasive health monitoring by analyzing sweat biomarkers like pH, K+, and Na+. This wearable sensor overcomes limitations of traditional devices for continuous, in situ perspiration analysis.
Area of Science:
- Biomedical Engineering
- Wearable Technology
- Analytical Chemistry
Background:
- Stretchable sweat sensors are vital for noninvasive health monitoring but face challenges with high fabrication costs and skin adhesion for microfluidic systems.
- Current devices require adhesives and struggle with controlled sweat sampling, limiting their practical application.
- The need for cost-effective and efficient sweat analysis platforms for continuous health monitoring is growing.
Purpose of the Study:
- To develop a stretchable and smart wettable patch for multiplexed in situ perspiration analysis.
- To overcome the limitations of high fabrication costs and skin adhesive requirements in existing sweat sensor technologies.
- To enable continuous, noninvasive monitoring of multiple sweat biomarkers during physical activity.
Main Methods:
- Fabrication of a stretchable patch with a porous microfoam membrane and nanofiber layer for selective sweat extraction.
- Integration of an electrochemical sensor array for simultaneous measurement of pH, K+, and Na+.
- Testing the patch's deformability (up to 50% strain) and its operating mode for sweat accumulation during exercise.
Main Results:
- The proposed patch successfully extracts sweat selectively and directs its flow for analysis.
- The device demonstrates stable and seamless integration with the skin due to its high deformability.
- Multiplexed electrochemical analysis of key biomarkers (pH, K+, Na+) was achieved in situ during continuous exercise.
- The smart wettable membrane proved effective in addressing sweat sampling challenges.
Conclusions:
- The developed stretchable and smart wettable patch offers an affordable and effective solution for in situ perspiration analysis.
- This technology advances wearable health monitoring by enabling continuous, noninvasive, and multiplexed analysis of sweat biomarkers.
- The patch's design overcomes key limitations of previous sweat sensor systems, paving the way for broader adoption.
