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Familial anetoderma.

S J Friedman, P Y Venencie, R R Bradley

Journal of the American Academy of Dermatology

|February 1, 1987

Summary

This summary is machine-generated.

Familial anetoderma, a rare skin condition, was observed in two families. The disease was limited to the skin, with no other systemic abnormalities found in affected individuals.

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Area of Science:

Dermatology
Genetics

Background:

Anetoderma is a rare skin condition characterized by the formation of sac-like herniations of the skin.
Familial occurrence of anetoderma has been reported, often associated with systemic abnormalities.

Observation:

Two families presented with anetoderma.
In these families, the anetoderma appeared to be an isolated skin finding.
No ocular, gastrointestinal, or orthopedic anomalies were noted in affected individuals or their relatives.

Findings:

The described cases suggest that familial anetoderma can manifest solely as a cutaneous disorder.
This contrasts with previous reports linking familial anetoderma to broader systemic involvement.

Implications:

Patients with familial anetoderma should be evaluated for potential systemic involvement, even if the condition appears isolated.
Further research is needed to understand the genetic basis and phenotypic variability of anetoderma.