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Published on: June 11, 2012
High concordance of blood glucose measurement in cats between a beta prototype glucometer device and a reference
Alex Walker1, Samuel D Stewart2
11Massachusetts Veterinary Referral Hospital, Ethos Veterinary Health, Woburn, MA.
Objective:
The objective of this study was to evaluate the accuracy of a beta prototype version of a new portable blood glucose meter in feline patients.
Animals:
60 client-owned cats.
Methods:
In this prospective study, 3-mL blood samples were collected from each cat and analyzed in triplicate using a beta prototype device (AlphaTRAK 3 [AT3]) and by a reference lab standard immediately after collection. Accuracy of the AT3 device was determined in accordance with the International Organization of Standardization (ISO) 15197:2013 criteria, including Bland-Altman plotting and consensus error grid analysis. A Passing-Bablok regression analysis was also performed.
Results:
96% of feline measurements fell within the ISO accuracy threshold, and 100% of measurements fell within zones A and B of the consensus error grid, meeting the ISO accuracy requirements. There was no significant bias in the data according to the Bland-Altman analysis. Within the full range of glucose concentrations (20 to 750 mg/dL) the correlation coefficient between the AT3 and the reference lab standard was 0.99. There was no significant constant or proportional bias present in the data.
Clinical Relevance:
The AT3 device met the ISO requirements and is accurate for measurement of blood glucose concentrations in cats.
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