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An Evaluation of Anatomic Referencing for Femoral Component Sizing Using Computed Tomography-Based Computer Modeling
Brett Campbell1, Max Weinberg2, Jeffrey Bischoff3
1Department of Orthopedic Surgery, Penn State Health, St. Joe's Medical Center, Reading, Pennsylvania.
The Journal of Knee Surgery
|January 8, 2024
Summary
Anatomic referencing with 2mm incremental femoral sizes in knee replacement allows precise component placement, aligning the anterior flange to the cortex and restoring posterior condylar offset within 1mm.
Area of Science:
- Orthopedic surgery
- Biomechanical engineering
- Medical device design
Background:
- Traditional femoral component sizing in total knee arthroplasty used anterior referencing (AR) and posterior referencing (PR) due to size variability.
- Smaller increments in femoral component sizes have led to the development of anatomic referencing.
Purpose of the Study:
- To validate the concept of anatomic referencing for femoral component placement.
- To demonstrate that 2mm incremental femoral sizes can achieve anterior cortical flushness and restore posterior condylar offset (PCO).
Main Methods:
- Created digital surface models of 515 femurs from CT scans.
- Performed virtual bone resections, component sizing (2mm increments), and placement.
- Assessed component positioning against the anterior cortex and measured posterior condylar gaps.
Main Results:
- Anatomic referencing with 2mm increments allowed femoral components to be placed flush with the anterior cortex, restoring PCO.
- The average medial gap was 0.6mm, and the overall average condylar gap was 1.02mm.
- The medial condyle was the limiting factor in 73% of cases.
Conclusions:
- Anatomic referencing with 2mm incremental sizing is a viable alternative to AR and PR for total knee arthroplasty.
- This method ensures accurate anterior flange alignment and PCO restoration without compromising fit.
- It eliminates the need to choose between AR or PR when between standard femoral sizes.

