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Ideal cardiovascular health metrics have better identification of arthritis

Yuxiang Wang1, Mengzi Sun1, Nan Yao1

  • 1Department of Epidemiology and Biostatistics, School of Public Health, Jilin University, 1163 Xinmin Avenue, 130021, Changchun, P. R. China.

BMC Public Health
|January 8, 2024
PubMed

Insights

Achieving ideal cardiovascular health metrics (ICVHM) significantly reduces arthritis risk. Higher ICVHM scores offer protective benefits against arthritis (AR) and its subtypes in US adults.

Area of Science:

  • Cardiovascular Health
  • Rheumatology
  • Public Health

Background:

  • Cardiovascular health is crucial for overall well-being.
  • Arthritis (AR) encompasses various joint conditions like osteoarthritis and rheumatoid arthritis.
  • Understanding the link between cardiovascular health and arthritis is vital for prevention strategies.

Purpose of the Study:

  • To investigate the association between ideal cardiovascular health metrics (ICVHM) and arthritis (AR) in US adults.
  • To explore interactions among ICVHM indicators in relation to AR.
  • To provide insights for arthritis identification and prevention.

Main Methods:

  • Analysis of 17,041 participants from NHANES (2011-2018).
  • Categorization of arthritis into osteoarthritis, rheumatoid arthritis, and other forms.
  • Application of logistic regression and mixed graphical models (MGM) to assess associations and interactions.

Main Results:

  • Higher ICVHM scores demonstrated a significant protective effect against AR (ORs ranging from 0.586 to 0.130).
  • This protective association was consistent across different types of arthritis.
  • ICVHM showed a strong predictive capability (AUC=0.765), with notable interactions between blood pressure and total cholesterol.

Conclusions:

  • Ideal cardiovascular health metrics are significantly correlated with reduced arthritis prevalence.
  • ICVHM is a more effective indicator for arthritis than individual metrics.
  • Targeting modifiable cardiovascular risk factors with strong interactions can enhance arthritis prevention efforts.
Abstract

Keywords:
ArthritisDifferent types of arthritisForest plotIdeal Cardiovascular Health MetricsMixed graphical model

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