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Reduction of CACNA1D-Associated Catatonia Symptoms in an Adolescent With Concurrent Severe Autism Spectrum Disorder: A Case Report.

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Catatonia in Preadolescent Children.

Lara De Stefano1, Alexander Palffy, Neera Ghaziuddin

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Summary
This summary is machine-generated.

Prepubescent catatonia, often overlooked, is linked to neurodevelopmental disorders and regression in young children. Early recognition is crucial for timely and effective treatment of this condition.

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Area of Science:

  • Pediatric Neurology
  • Child Psychiatry

Background:

  • Catatonia in prepubescent children is under-documented and frequently missed in clinical settings.
  • This study addresses the gap in understanding early-onset catatonia.

Purpose of the Study:

  • To describe the characteristics of catatonia in very young children.
  • To highlight the diagnostic challenges and associated conditions in prepubescent catatonia.

Main Methods:

  • Retrospective review of 10 patients under 12 years old diagnosed with catatonia.
  • Data extracted from electronic medical records included demographics, comorbidities, developmental history, and treatment.
  • Bush Francis Catatonia Rating Scales were used to assess symptom severity.

Main Results:

  • 70% of patients had a prior diagnosis of autism spectrum disorder.
  • Comorbid conditions were present in all but one patient.
  • Regression was a noted symptom in all cases, irrespective of autism spectrum disorder diagnosis.

Conclusions:

  • Prepubescent catatonia shares similarities with adolescent presentations, including association with neurodevelopmental disorders, regression, and comorbidities.
  • Delayed diagnosis can impede prompt and effective treatment for catatonia in young children.