Single-port and multiport robot-assisted radical prostatectomy: A meta-analysis

Area of Science:

• Urology
• Surgical Oncology
• Robotic Surgery

Background:

• Robot-assisted radical prostatectomy (RARP) is a standard treatment for prostate cancer.
• Single-port (SP) and multiport (MP) approaches exist, with varying outcomes.
• Comparative analysis of SP-RARP versus MP-RARP is crucial for surgical decision-making.

Purpose of the Study:

• To compare perioperative, oncological, and functional outcomes between SP-RARP and MP-RARP.
• To evaluate the efficacy and safety of the single-port approach in radical prostatectomy.
• To provide evidence-based insights for choosing between SP-RARP and MP-RARP.

Main Methods:

• A systematic meta-analysis of studies comparing SP-RARP and MP-RARP.
• Searched PubMed, Scopus, and Web of Science databases up to January 15, 2022.
• Analyzed dichotomous and continuous variables using risk ratios and weighted mean differences with 95% confidence intervals.

Main Results:

• Seven studies with 1,934 patients (355 SP-RARP, 1,579 MP-RARP) were included.
• SP-RARP showed significantly less postoperative pain, lower opioid use, shorter hospital stays, and reduced catheterization time.
• SP-RARP had a longer console time compared to MP-RARP.

Conclusions:

• Early outcomes of SP-RARP are largely equivalent to MP-RARP.
• SP-RARP may reduce postoperative pain and hospital stay without negatively impacting functional or early oncological results.
• SP-RARP represents a viable alternative to MP-RARP for radical prostatectomy.