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Related Experiment Videos

Paraparesis in hereditary multiple exostoses: case report.

G Ferrari, L Taddei, C Vivenza

    Neurology
    |July 1, 1979
    PubMed
    Summary
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    Hereditary multiple exostoses (HME) can cause spinal cord compression, leading to neurologic deficits. Surgical decompression via laminectomy effectively treated a case of HME-induced spastic paraparesis.

    Area of Science:

    • Neurology
    • Orthopedics
    • Genetics

    Background:

    • Hereditary multiple exostoses (HME) is a rare genetic disorder characterized by the development of multiple bony outgrowths (exostoses).
    • Neurologic complications in HME are uncommon but can arise from direct compression by exostoses.
    • Spastic paraparesis and sphincter dysfunction are potential, severe manifestations of spinal cord involvement.

    Observation:

    • A 23-year-old male presented with progressive spastic paraparesis and sphincter dysfunction.
    • Clinical examination revealed no cranial nerve or sensory deficits.
    • Radiologic imaging confirmed the characteristic features of HME and identified an exostosis compressing the C2 spinal cord.

    Findings:

    • A C2 vertebral exostosis was identified as the cause of spinal cord compression.

    Related Experiment Videos

  • The patient underwent a laminectomy for surgical decompression.
  • Post-operative recovery showed rapid improvement in neurologic symptoms.

    • Implications:

    • This case highlights the importance of considering spinal cord compression in HME patients with neurologic symptoms.
    • Early diagnosis and surgical intervention are crucial for favorable outcomes.
    • Understanding the potential neurologic manifestations of HME aids in comprehensive patient management.