Bilateral, Simultaneous Central Serous Chorioretinopathy in Association With Oral Contraception Use

Area of Science:

• Ophthalmology
• Retinal Diseases
• Pharmacological Ophthalmology

Background:

• Central serous chorioretinopathy (CSCR) is a condition affecting the retina, often associated with stress or corticosteroid use.
• The role of exogenous hormones, such as oral contraceptive pills (OCP), in the pathogenesis of CSCR is not well-established.
• This case investigates a potential link between OCP use and the development of CSCR.

Observation:

• A 21-year-old woman presented with acute bilateral vision loss.
• The patient had recently initiated oral contraceptive pills (OCP).
• Ocular examination revealed bilateral central serous chorioretinopathy (CSCR).

Findings:

• Optical coherence tomography (OCT) and fluorescein angiography confirmed bilateral serous retinal detachments.
• Discontinuation of OCP resulted in complete resolution of visual symptoms within three weeks.
• Repeat OCT confirmed the resolution of retinal detachments, suggesting a direct impact of OCP withdrawal.

Implications:

• This case highlights a potential iatrogenic cause of CSCR in young women using OCP.
• Clinicians should consider OCP as a potential trigger for CSCR in susceptible individuals.
• Further research is warranted to explore the association between hormonal contraceptives and CSCR.