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Vocal fold cryptococcal granuloma: A rare occurrence in immunocompetent patient
Muhamamad Raziin Zainal Abidin1, Syarifah Nafisah Syed Hamzah Al-Yahya1, Masaany Mansor2
1Department of Otorhinolaryngology, Hospital Al-Sultan Abdullah UiTM, Bandar Puncak Alam, Selangor, Malaysia.
Introduction And Importance:
Cryptoccous infection or cryptococcosis is a severe opportunistic infection occurring mainly in immunocompromised patients. Laryngeal cryptococcus infection is rare. In an immunocompetent patient, inhaled corticosteroid was reported to be a possible risk factor.
Case Presentation:
We discuss a case of right vocal fold cryptococcus infection in a healthy, immunocompetent 71-year-old man with no history of inhaled corticosteroid, presented with hoarseness and intermittent aspiration symptom for 1 year duration. Further examination showed right anterior vocal fold mass with presence of right vallecular cyst.
Clinical Discussion:
Patient underwent direct laryngoscopy, excision of right vocal fold mass and marsupialization of vallecular cyst. Histopathological examination revealed cryptococcal infection. Patient subsequently treated with oral fluconazole 400 mg daily for 6 months. To date, hoarseness and aspiration symptoms have resolved.
Conclusion:
We are sharing our experience in managing laryngeal cryptococcus infection in an immunocompetent patient where the associated risk factors discussed in previous literatures are absent.
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