Optimizing Outcomes through a Multidisciplinary Team Approach in Endometrial Cancer

Area of Science:

• Oncology
• Cancer Research
• Clinical Medicine

Background:

• Endometrial cancer (EC) management requires comprehensive strategies.
• The impact of multidisciplinary team (MDT) approaches on EC patient outcomes is an area of ongoing investigation.
• Understanding patient demographic shifts is crucial for optimizing cancer care.

Purpose of the Study:

• To evaluate the effect of a multidisciplinary team (MDT) approach on endometrial cancer (EC) patient outcomes.
• To compare recurrence rates, treatments, and survival indicators between MDT and non-MDT groups.
• To analyze changes in patient demographics and their influence on EC management over time.

Main Methods:

• Retrospective analysis of 2013-2020 data from the Reggio Emilia Cancer Registry.
• Comparison of outcomes between 319 MDT-treated EC cases and 324 non-MDT-treated cases.
• Statistical analysis of recurrence rates, disease-free survival (DFS), and overall survival (OS).

Main Results:

• Recurrence rates were similar between MDT and non-MDT groups (10%).
• MDT patients, particularly older individuals in stage I, showed a higher one-year recurrence rate (79% vs. 21%).
• Overall survival (OS) was notably better in the MDT group (5-year OS: 87% vs. 79%), despite no significant difference in DFS.

Conclusions:

• The multidisciplinary team (MDT) approach demonstrates a positive impact on overall survival for endometrial cancer (EC) patients.
• Evolving patient demographics, including an increase in older and more advanced-stage patients, necessitate adaptive care strategies.
• Continued evaluation of MDT effectiveness is essential for improving EC patient outcomes.