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Updated: Jul 5, 2025

The Caco-2 Cell Bioassay for Measurement of Food Iron Bioavailability
Published on: April 28, 2022
Plant Iron Research in African Countries: Current "Hot Spots", Approaches, and Potentialities
Irene Murgia1, Piero Morandini1
1Department of Environmental Science and Policy, Università degli Studi di Milano, Via Celoria 10, 20133 Milan, Italy.
Abstract:
Plant iron (Fe) nutrition and metabolism is a fascinating and challenging research topic; understanding the role of Fe in the life cycle of plants requires knowledge of Fe chemistry and biochemistry and their impact during development. Plant Fe nutritional status is dependent on several factors, including the surrounding biotic and abiotic environments, and influences crop yield and the nutritional quality of edible parts. The relevance of plant Fe research will further increase globally, particularly for Africa, which is expected to reach 2.5 billion people by 2050. The aim of this review is to provide an updated picture of plant Fe research conducted in African countries to favor its dissemination within the scientific community. Three main research hotspots have emerged, and all of them are related to the production of plants of superior quality, i.e., development of Fe-dense crops, development of varieties resilient to Fe toxicity, and alleviation of Fe deficiency, by means of Fe nanoparticles for sustainable agriculture. An intensification of research collaborations between the African research groups and plant Fe groups worldwide would be beneficial for the progression of the identified research topics.

