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Published on: November 21, 2013
Racial Disparities Among Clinical High-Risk and First-Episode Psychosis Multisite Research Participants: A Systematic
Timothy I Michaels1, Laura Simon-Pearson1, John M Kane1
1Division of Psychiatry Research, Zucker Hillside Hospital, Northwell Health, Glen Oaks, New York (Michaels, Simon-Pearson, Cornblatt); Department of Psychiatry, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York (Michaels, Kane); Department of Psychology, Hofstra University, Hempstead, New York (Simon-Pearson); Institute of Behavioral Science (Kane) and Center for Psychiatric Neuroscience (Cornblatt), Feinstein Institute for Medical Research, Northwell Health, Manhasset, New York.
Inclusion of Black, Indigenous, and people of color (BIPOC) in psychosis research is high, particularly in first-episode psychosis (FEP) studies. However, further efforts are needed to enhance ethnoracial diversity in clinical high-risk studies.
Area of Science:
- Psychiatry
- Clinical Research
- Health Equity
Background:
- The National Institutes of Health (NIH) mandates equal representation of Black, Indigenous, and people of color (BIPOC) in clinical research.
- Understanding ethnoracial inclusion in psychosis research is crucial for addressing social determinants of psychosis and risk.
Approach:
- A systematic review of multisite studies on clinical high risk for psychosis and first-episode psychosis (FEP) in North America (1993-2022) was conducted.
- 12 studies met inclusion criteria, with data analyzed for demographics, socioeconomic status, study design, and recruitment strategies.
Key Points:
- In clinical high-risk studies, 62% of participants were White, with representation across most ethnoracial groups comparable to national data.
- In FEP studies, Black participants constituted the largest ethnoracial group (43%) and were overrepresented compared to the U.S. population.
- FEP studies more frequently recruited from community mental health centers than clinical high-risk studies.
Conclusions:
- While BIPOC representation in psychosis research is substantial, particularly in FEP, opportunities exist to improve ethnoracial diversity.
- Recommendations are provided to enhance ethnoracial diversity in future psychosis research samples.
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