Related Experiment Video
Updated: Jul 5, 2025

Ultrasonic Assessment of Myocardial Microstructure
Published on: January 14, 2014
The "Lightbulb" Sign: A Novel Echocardiographic Finding Using Ultrasound Enhancing Agent in Fulminant
Ayana Nanthakumar1, Mali Worme1, Tahseen Rahman2
1Division of Cardiology, University Health Network, Toronto, Ontario, Canada.
Insights
Fulminant COVID-19 myocarditis cases may show a new "lightbulb" sign on echocardiograms. Ultrasound-enhancing agents can help identify this finding, aiding in myocarditis diagnosis.
Area of Science:
- Cardiology
- Infectious Diseases
- Medical Imaging
Background:
- COVID-19 can cause severe cardiac complications, including fulminant myocarditis.
- Myocarditis diagnosis often relies on imaging, but specific echocardiographic findings can be challenging.
- Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is a critical support for severe cases.
Observation:
- A case of severe COVID-19-related myocarditis requiring VA-ECMO was analyzed.
- Ultrasound-enhancing agents were utilized during echocardiography.
Findings:
- A novel echocardiographic finding, termed the "lightbulb" sign, was observed.
- This sign was visualized using ultrasound-enhancing agents.
Implications:
- The "lightbulb" sign may serve as a new diagnostic indicator for myocarditis.
- Ultrasound-enhancing agents could play a more significant role in echocardiographic diagnosis of inflammatory cardiac conditions.
- Further research is warranted to validate the "lightbulb" sign in broader patient cohorts.
Abstract:
We report a case of fulminant COVID-19-related myocarditis requiring venoarterial extracorporeal membrane oxygenation where the use of an ultrasound-enhancing agent demonstrated a previously undescribed echocardiographic finding, the "lightbulb" sign. This sign potentially represents a new area for the use of an ultrasound enhancing agent in the echocardiographic diagnosis of myocarditis.
More Related Videos
07:33Bioluminescence Imaging for Assessment of Immune Responses Following Implantation of Engineered Heart Tissue EHT
Published on: June 1, 2011
08:05Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
Published on: December 19, 2020
Related Concept Videos
Imaging Studies for Cardiovascular System II:Types of Echocardiography
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for...
Imaging Studies for Cardiovascular System I:Echocardiography
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion,...
Imaging Studies for Cardiovascular System III: X-Ray
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
Electrocardiogram
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and...
Blood Studies for Cardiovascular System I: Cardiac Biomarkers
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...