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Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
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Prepectoral and Retropectoral Breast-implant-Associated Anaplastic Large-cell Lymphoma
Gonzalo Ziegler-Rodriguez1,2,3, Milko Garces-Ruiz1,3, Gabriel De La Cruz-Ku4,5
1From the Instituto Nacional de Enfermedades Neoplasicas (INEN), Lima, Peru.
Plastic and Reconstructive Surgery. Global Open
|January 11, 2024
Summary
Breast-implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a rare cancer. This study presents the first two Peruvian cases, highlighting BIA-ALCL
Area of Science:
- Oncology
- Hematology
- Medical Devices
Background:
- Breast-implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a rare T-cell lymphoma.
- It is associated with breast implants, developing in the peri-implant capsule.
- Over 1000 cases reported globally since its initial description.
Purpose of the Study:
- To report the first two cases of BIA-ALCL diagnosed and treated in Peru.
- To illustrate the diagnostic and treatment approaches for BIA-ALCL in a new geographical context.
- To highlight the variable clinical presentation and aggressiveness of BIA-ALCL.
Main Methods:
- Case report of two patients diagnosed with BIA-ALCL.
- Review of diagnostic procedures including imaging and biopsy.
- Description of treatment strategies employed for each case.
Main Results:
- Two distinct cases of BIA-ALCL were successfully diagnosed and managed in Peru.
- The cases demonstrated a spectrum of disease aggressiveness.
- Treatment outcomes were consistent with established BIA-ALCL management protocols.
Conclusions:
- BIA-ALCL diagnosis and treatment are feasible in Peru.
- The disease exhibits variable aggressiveness, necessitating tailored management.
- This report expands the geographical data on BIA-ALCL incidence and clinical behavior.

